| # | Unlocked | Locked | Name | Beschreibung | Spieler | Global |
|---|---|---|---|---|---|---|
| 1 |
|
| Hard to Stomach | 1 | 70.2% | |
| 2 |
|
| Overserving | No inmate left untreated for an entire day | 1 | 70% |
| 3 |
|
| Sweeten the Pills | Serve 50 Pills in one playthrough | 0 | 54.8% |
| 4 |
|
| In Everyone's Veins | Administer 20 Drips in one playthrough | 0 | 44.2% |
| 5 |
|
| (Do not) Choose your Poison | 0 | 43.1% | |
| 6 |
|
| Assisted Corruption | 0 | 31.8% | |
| 7 |
|
| Someone's Lucky Day | 0 | 29.1% | |
| 8 |
|
| "Me Pippi" | 0 | 28.7% | |
| 9 |
|
| Madness & Monsters | 0 | 28.3% | |
| 10 |
|
| Oliver Twist | 0 | 26.7% | |
| 11 |
|
| Pippimonium | 0 | 25.7% | |
| 12 |
|
| Heart in the Wrong Place | 0 | 19.4% | |
| 13 |
|
| A Friend Indeed | 0 | 17.8% | |
| 14 |
|
| Wicked Angel | 0 | 17.5% | |
| 15 |
|
| The Kindeman Reward | 0 | 15.2% | |
| 16 |
|
| The All-doctor | Unlock all the upgrades in one playthrough | 0 | 14.3% |
| 17 |
|
| Dies Irae | 0 | 5.1% | |
| 18 |
|
| No Gain, All Pain | 0 | 3.7% | |
| 19 |
|
| Eureka | Complete one playthrough with 100% of the Remedy | 0 | 2.9% |
| 20 |
|
| The Kindeman Risk | 0 | 2.7% | |
| 21 |
|
| Pain Specialist | Use all "Special Treatments" in one playthrough | 0 | 1.7% |
| 22 |
|
| The Kindeman Riot | 0 | 1.2% |